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Mutations in the MECP2 gene, located at the end of the longer arm of the chromosome X (Xq28), are involved in the development of Rett syndrome

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This short-lived ROS can combine with nitric oxide (NO · ) to form the highly reactive peroxynitrite (a reactive nitrogen species [RNS]) or can spontaneously or enzymatically be dismutated to form hydrogen peroxide and molecular oxygen (59, 232)