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12.2 and 18.2 percent at 9 and 12 mg vs 4.0 percent in TRIUMPH-4 Months 3-6: Peak Results Phase 2, 24 weeks: least-squares mean weight change -7.2 percent (1 mg), -12.9 percent (4 mg), -17.3 percent (8 mg), -17.5 percent (12 mg) vs -1.6 percent placebo (NEJM 2023) TRIUMPH-2, adults with type 2 diabetes, 80 weeks: A1C fell 1.4, 1.6 and 1.5 percentage points at 4, 9 and 12 mg (Lilly, July 23, 2026) Phase 2: dose-dependent increases in heart rate peaked at 24 weeks (NEJM 2023) Months 6-12: Sustained Progress Phase 2, 48 weeks: -8.7 percent (1 mg), -17.1 percent (4 mg), -22.8 percent (8 mg), -24.2 percent (12 mg) vs -2.1 percent placebo

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Photographs for baseline