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Five experts interviewed said they had direct knowledge that private water treatment plants were not adding enough chlorine or in some cases not adding any chlorine at all in order to save on costs.[180] In addition, as one aid worker in the water sector explained, many RO plants use UV or ozone technology to purify water instead of chlorine because it is cheaper, even though these processes cannot guard against harmful substances that enter the water later, for example, in a water tank.[181] There is no definitive proof that anyone fell ill from filtered water from the private water sector during the 2018 crisis, but several interviewees told Human Rights Watch they believed they or their relatives have gotten sick from RO water, and others emphasized that water could only be purchased from specific plants, because not all plants could be trusted.[182] A health sector employee from Abu al-Khasib said that seven of his family members got sick during the 2018 crisis even though they were only using RO water including for washing fruits and vegetables and dishes, leading him to suspect that the RO plant might not be treating the water sufficiently or that the trucks in which it was transported were contaminated.[183] Mehdi Hamid Silan, a laborer from an area called Salhiya, said that he and other families buy filtered water for drinking and cooking, but that he regularly gets stomach pains from that water as well and does not think it is properly treated

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NNMT consumes SAM (S-adenosylmethionine) to methylate nicotinamide, producing 1-methylnicotinamide, which reduces NAD+ bioavailability in tissues